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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2000-8-22
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pubmed:abstractText |
Major depression and suicide are associated with fewer serotonin transporter (5-HTT) sites. The 5'-flanking promoter region of the 5-HTT gene has a biallelic insertion/deletion (5-HTTLPR). We assayed prefrontal cortical (PFC) 5-HTT binding in major depression and suicide and examine the relationship to the 5-HTTLPR allele.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0003-990X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
729-38
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10920459-Adult,
pubmed-meshheading:10920459-Autoradiography,
pubmed-meshheading:10920459-Carrier Proteins,
pubmed-meshheading:10920459-Depressive Disorder,
pubmed-meshheading:10920459-Female,
pubmed-meshheading:10920459-Gene Expression,
pubmed-meshheading:10920459-Genotype,
pubmed-meshheading:10920459-Humans,
pubmed-meshheading:10920459-Male,
pubmed-meshheading:10920459-Membrane Glycoproteins,
pubmed-meshheading:10920459-Membrane Transport Proteins,
pubmed-meshheading:10920459-Mental Disorders,
pubmed-meshheading:10920459-Middle Aged,
pubmed-meshheading:10920459-Nerve Tissue Proteins,
pubmed-meshheading:10920459-Polymorphism, Genetic,
pubmed-meshheading:10920459-Prefrontal Cortex,
pubmed-meshheading:10920459-Promoter Regions, Genetic,
pubmed-meshheading:10920459-Serotonin,
pubmed-meshheading:10920459-Serotonin Plasma Membrane Transport Proteins,
pubmed-meshheading:10920459-Sex Factors,
pubmed-meshheading:10920459-Suicide
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pubmed:year |
2000
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pubmed:articleTitle |
A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide.
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pubmed:affiliation |
Department of Neuroscience, New York State Psychiatric Institute, New York 10032, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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