rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-8-10
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pubmed:abstractText |
A rat pancreas transplantation model with insulin-dependent diabetes mellitus (IDDM) recurrence was established using a Wistar-Furth (WF; RT1u, RT6.2) rat as a donor and diabetes-prone (DP; RT1u, rt6.1 gene carrier) BioBreeding rat as a recipient. Interestingly, NKR-P1+TCRalphabeta+ (NKT) cells have recently been reported to have immunoregulatory functions in preventing autoimmune diabetes. The purpose of this study was to specifically examine the contribution of NKT cells in the prevention of IDDM recurrence.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ADP Ribose Transferases,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Art2a protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Art2b protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Art2b protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-4,
http://linkedlifedata.com/resource/pubmed/chemical/Lectins, C-Type,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/NK Cell Lectin-Like Receptor...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, T-Cell...
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
32-8
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pubmed:dateRevised |
2009-9-7
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pubmed:meshHeading |
pubmed-meshheading:10919571-ADP Ribose Transferases,
pubmed-meshheading:10919571-Animals,
pubmed-meshheading:10919571-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:10919571-Antigens, Surface,
pubmed-meshheading:10919571-Diabetes Mellitus, Type 1,
pubmed-meshheading:10919571-Duodenum,
pubmed-meshheading:10919571-Flow Cytometry,
pubmed-meshheading:10919571-Interleukin-4,
pubmed-meshheading:10919571-Islets of Langerhans Transplantation,
pubmed-meshheading:10919571-Lectins, C-Type,
pubmed-meshheading:10919571-Male,
pubmed-meshheading:10919571-Membrane Glycoproteins,
pubmed-meshheading:10919571-Mice,
pubmed-meshheading:10919571-NK Cell Lectin-Like Receptor Subfamily B,
pubmed-meshheading:10919571-Pancreas Transplantation,
pubmed-meshheading:10919571-Rats,
pubmed-meshheading:10919571-Rats, Inbred WF,
pubmed-meshheading:10919571-Receptors, Antigen, T-Cell, alpha-beta,
pubmed-meshheading:10919571-Recurrence,
pubmed-meshheading:10919571-T-Lymphocytes
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pubmed:year |
2000
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pubmed:articleTitle |
Importance of donor-derived lymphocytes in the protection of pancreaticoduodenal or islet grafts from recurrent autoimmunity: a role for RT6+NKR-P1+ T cells.
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pubmed:affiliation |
Department of Bioregulation, Biomedical Research Center, Osaka University Graduate School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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