Source:http://linkedlifedata.com/resource/pubmed/id/10918431
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-11-3
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pubmed:abstractText |
Using a real-time quantitative PCR assay, we identified two patients with EBV-related lymphoproliferative disorders at a very early stage. Both had received an unmanipulated bone marrow transplant with anti-thymocyte globulin for conditioning. To estimate virus-specific immunity, the frequencies of EBV-specific CD8+ T cells were measured using an enzyme-linked immunospot assay. The frequencies of EBV-specific CD8+ T cells of the two were 3.2 and 7.7%, respectively, which had possibly expanded in vivo. After withdrawing the immunosuppressive agents or administering donor lymphocytes transfusion, their symptoms regressed in parallel with the viral load.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0268-3369
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-201
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10918431-Adult,
pubmed-meshheading:10918431-Bone Marrow Transplantation,
pubmed-meshheading:10918431-CD8-Positive T-Lymphocytes,
pubmed-meshheading:10918431-Child,
pubmed-meshheading:10918431-DNA, Viral,
pubmed-meshheading:10918431-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10918431-Epstein-Barr Virus Infections,
pubmed-meshheading:10918431-Female,
pubmed-meshheading:10918431-Herpesvirus 4, Human,
pubmed-meshheading:10918431-Humans,
pubmed-meshheading:10918431-Lymphoproliferative Disorders,
pubmed-meshheading:10918431-Viral Load
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pubmed:year |
2000
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pubmed:articleTitle |
Early intervention in post-transplant lymphoproliferative disorders based on Epstein-Barr viral load.
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pubmed:affiliation |
Department of Pediatrics, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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