Source:http://linkedlifedata.com/resource/pubmed/id/10918194
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2000-8-18
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pubmed:abstractText |
To assess the prevalence and incidence of human T-cell lymphotropic virus type I (HTLV-I), 4,234 pregnant women of different ethnic origins were tested before each delivery between 1991 and 1997 in a high HTLV-I endemic area of French Guiana. HTLV-I was significantly more prevalent among ethnic groups of African descent as the Noir-Marrons (4.8%, 95% confidence interval [CI]: 4.0-5.6) and Haitians (5%, 95% CI 1.6-8.4). An age dependence of HTLV-I seroprevalence was observed. The mean age of Noir-Marron HTLV-I seronegative women was lower than for HTLV-I seropositive women (24. 7 vs. 28.6, p < 0.001). A decline in HTLV-I seroprevalence was observed, particularly in the Noir-Marron younger than 21 years old (p = 0.04). For five HTLV-I seroconversions observed, the incidence per 100 women-years in the Noir-Marron group was 0.19 (95% CI 0.02-0. 35) for all women, 0.32 in those 25 years old or younger (95% CI 0-0. 64), and 0.07 in those older than 25 years (95% CI 0-0.2). This observation was inconsistent with HTLV-I seroprevalence observed for those 25 years old or younger (2.8%) and those older than 25 (8.3%). These data demonstrate, for the first time outside Japan, a birth cohort effect for HTLV-I in a highly endemic ethnic group.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0020-7136
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
534-8
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pubmed:dateRevised |
2007-7-24
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pubmed:meshHeading |
pubmed-meshheading:10918194-Adult,
pubmed-meshheading:10918194-Africa,
pubmed-meshheading:10918194-Endemic Diseases,
pubmed-meshheading:10918194-Female,
pubmed-meshheading:10918194-French Guiana,
pubmed-meshheading:10918194-HTLV-I Infections,
pubmed-meshheading:10918194-Human T-lymphotropic virus 1,
pubmed-meshheading:10918194-Humans,
pubmed-meshheading:10918194-Incidence,
pubmed-meshheading:10918194-Pregnancy,
pubmed-meshheading:10918194-Pregnancy Complications, Infectious,
pubmed-meshheading:10918194-Prevalence,
pubmed-meshheading:10918194-Seroepidemiologic Studies
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pubmed:year |
2000
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pubmed:articleTitle |
Decrease of human T-cell lymphotropic virus type I prevalence and low incidence among pregnant women from a high endemic ethnic group in French Guiana.
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pubmed:affiliation |
Unité d'Epidémiologie des Virus Oncogènes, Institut Pasteur, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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