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rdf:type |
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lifeskim:mentions |
umls-concept:C0013030,
umls-concept:C0034693,
umls-concept:C0205216,
umls-concept:C0221099,
umls-concept:C0580836,
umls-concept:C0597421,
umls-concept:C0678226,
umls-concept:C0871261,
umls-concept:C1704259,
umls-concept:C1704632,
umls-concept:C1705987,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
2
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pubmed:dateCreated |
2000-9-7
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pubmed:abstractText |
Dopamine (DA) causes natriuresis and diuresis, which results from activation of D1-like receptor (D1R) located on proximal tubules. Earlier, we reported that DA failed to inhibit Na,K-ATPase in proximal tubules of old Fischer 344 rats. The present study was designed to investigate the functional consequence of this phenomenon.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,3,4,5-Tetrahydro-7,8-dihydroxy-1-p...,
http://linkedlifedata.com/resource/pubmed/chemical/Adenylate Cyclase,
http://linkedlifedata.com/resource/pubmed/chemical/Cardiotonic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP-Dependent Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/GTP-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Guanosine 5'-O-(3-Thiotriphosphate),
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Dopamine D1,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium-Hydrogen Antiporter,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfur Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Tritium
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
712-20
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10916094-2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine,
pubmed-meshheading:10916094-Adenylate Cyclase,
pubmed-meshheading:10916094-Age Factors,
pubmed-meshheading:10916094-Aging,
pubmed-meshheading:10916094-Animals,
pubmed-meshheading:10916094-Cardiotonic Agents,
pubmed-meshheading:10916094-Cyclic AMP-Dependent Protein Kinases,
pubmed-meshheading:10916094-Dopamine,
pubmed-meshheading:10916094-Dopamine Agonists,
pubmed-meshheading:10916094-GTP-Binding Proteins,
pubmed-meshheading:10916094-Guanosine 5'-O-(3-Thiotriphosphate),
pubmed-meshheading:10916094-Homeostasis,
pubmed-meshheading:10916094-Kidney Tubules, Proximal,
pubmed-meshheading:10916094-Male,
pubmed-meshheading:10916094-Natriuresis,
pubmed-meshheading:10916094-Radioligand Assay,
pubmed-meshheading:10916094-Rats,
pubmed-meshheading:10916094-Rats, Inbred F344,
pubmed-meshheading:10916094-Receptors, Dopamine D1,
pubmed-meshheading:10916094-Signal Transduction,
pubmed-meshheading:10916094-Sodium,
pubmed-meshheading:10916094-Sodium-Hydrogen Antiporter,
pubmed-meshheading:10916094-Sulfur Radioisotopes,
pubmed-meshheading:10916094-Tritium
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pubmed:year |
2000
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pubmed:articleTitle |
Diminished natriuretic response to dopamine in old rats is due to an impaired D1-like receptor-signaling pathway.
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pubmed:affiliation |
Institute for Cardiovascular Studies, College of Pharmacy, University of Houston, TX 77204-5511, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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