Linked Life Data

10915880

Source:http://linkedlifedata.com/resource/pubmed/id/10915880

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
18
pubmed:dateCreated
2000-9-15
pubmed:abstractText
Exposure to continuous illumination disrupts normal ocular development in young chicks, causing severe corneal flattening, shallow anterior chambers and progressive hyperopia ('constant light (CL) effects'). We have studied the minimum requirements of a diurnal light cycle to prevent CL effects. (1) Seven groups of 10 chicks were reared under a 0 (constant light, CL), or 1, 2, 3,4, 6, or 12/12 h (normal) light-dark cycles. It was found that CL effects were prevented if the dark period was 4 h or longer. Below 4 h, the effects were dose-dependent and inversely correlated with the amplitude of the Fourier component of illumination at 1 cycle per day (CPD). (2) Three groups of 20 chicks were exposed to 4 h of darkness distributed differently over 24 h to vary the amplitude of the Fourier component at 1 CPD. It was found that complete suppression of the CL effects required that the 4 h of darkness were given in one block and at the same time each day. Our results show that normal ocular development in the chick requires a minimum of 4 h darkness per day, provided at the same time of the day without interruption, and suggest that the light-dark cycle interacts with a linear or weakly nonlinear oscillating system.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0042-6989
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2387-93
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Diurnal illumination patterns affect the development of the chick eye.
pubmed:affiliation
Section of Neurobiology and Behavior, Cornell University, 14853, Ithaca, NY, USA. tl24@cornell.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.