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rdf:type |
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lifeskim:mentions |
umls-concept:C0003250,
umls-concept:C0024337,
umls-concept:C0185125,
umls-concept:C0220825,
umls-concept:C0242606,
umls-concept:C0439098,
umls-concept:C0596577,
umls-concept:C1280500,
umls-concept:C1515075,
umls-concept:C1521827,
umls-concept:C1882854
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pubmed:issue |
2
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pubmed:dateCreated |
2000-8-24
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pubmed:abstractText |
The monoclonal antibody to N(epsilon)-(hexanonyl)lysine (HEL), a novel adduct formed by the reaction of linoleic acid hydroperoxide and lysine, has been prepared and characterized. The obtained antibody specifically recognized the HEL moiety. Using the monoclonal antibody, we evaluated the protective effects of feeding eriocitrin, which is one of flavonoids in lemon fruit, on oxidative modification induced by exercise in rats. The supplementation of eriocitrin significantly suppressed the increase in HEL in the skeletal muscle by exercise. The result suggests that the determination of HEL may be a good method for evaluation of the protective effect of beneficial food factors against oxidative stress.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Aldehydes,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Carbodiimides,
http://linkedlifedata.com/resource/pubmed/chemical/Flavanones,
http://linkedlifedata.com/resource/pubmed/chemical/Flavonoids,
http://linkedlifedata.com/resource/pubmed/chemical/Hesperidin,
http://linkedlifedata.com/resource/pubmed/chemical/Hexanoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Lipid Peroxides,
http://linkedlifedata.com/resource/pubmed/chemical/Lysine,
http://linkedlifedata.com/resource/pubmed/chemical/N(epsilon)-hexanoyllysine,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin, Bovine,
http://linkedlifedata.com/resource/pubmed/chemical/eriocitrin,
http://linkedlifedata.com/resource/pubmed/chemical/hexanoic acid
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2000 Academic Press.
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pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
274
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
389-93
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10913348-Aldehydes,
pubmed-meshheading:10913348-Animals,
pubmed-meshheading:10913348-Antibodies, Monoclonal,
pubmed-meshheading:10913348-Carbodiimides,
pubmed-meshheading:10913348-Dietary Supplements,
pubmed-meshheading:10913348-Female,
pubmed-meshheading:10913348-Flavanones,
pubmed-meshheading:10913348-Flavonoids,
pubmed-meshheading:10913348-Hesperidin,
pubmed-meshheading:10913348-Hexanoic Acids,
pubmed-meshheading:10913348-Lipid Peroxides,
pubmed-meshheading:10913348-Lysine,
pubmed-meshheading:10913348-Mice,
pubmed-meshheading:10913348-Mice, Inbred BALB C,
pubmed-meshheading:10913348-Muscle, Skeletal,
pubmed-meshheading:10913348-Oxidative Stress,
pubmed-meshheading:10913348-Physical Exertion,
pubmed-meshheading:10913348-Rats,
pubmed-meshheading:10913348-Rats, Sprague-Dawley,
pubmed-meshheading:10913348-Serum Albumin, Bovine
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pubmed:year |
2000
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pubmed:articleTitle |
Preparation of a monoclonal antibody to N(epsilon)-(Hexanonyl)lysine: application to the evaluation of protective effects of flavonoid supplementation against exercise-induced oxidative stress in rat skeletal muscle.
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pubmed:affiliation |
School of Humanities for Environmental Policy and Technology, Himeji Institute of Technology, Himeji, 670-0092, Japan.
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pubmed:publicationType |
Journal Article
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