Linked Life Data

10911400

Source:http://linkedlifedata.com/resource/pubmed/id/10911400

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-10-25
pubmed:abstractText
Centrosome reduction during spermiogenesis has been studied using anti-gamma-tubulin and anti-centrin antibodies and electron microscopy in nonhuman primates. Rhesus spermatids possess apparently normal centrosomes comprising a pair of centrioles associated with gamma-tubulin and centrin. However, they do not nucleate detectable microtubules. The spermatids discard gamma-tubulin in the residual bodies during the spermiation stage. Mature sperm do not have any detectable gamma-tubulin. About half of the centrin associated with the distal centriole degenerates during spermiogenesis and the remainder is intimately bound to the centriolar microtubules. The mature sperm possess highly degenerated distal centrioles. The centriolar microtubules degenerate in the rostral region and the ventral side of the sperm. The study indicates that the centrosome is reduced during rhesus spermiogenesis, but not completely as in mice.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1040-452X
pubmed:author
pubmed:issnType
Print
pubmed:volume
56
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
502-11
pubmed:dateRevised
2005-6-6
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Centrosome reduction during Rhesus spermiogenesis: gamma-tubulin, centrin, and centriole degeneration.
pubmed:affiliation
Department of Cell & Developmental Biology, Oregon Regional Primate Research Center/Oregon Health Science University, Beaverton 97006, USA.
pubmed:publicationType
Journal Article