Source:http://linkedlifedata.com/resource/pubmed/id/10908079
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-11-2
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pubmed:abstractText |
To investigate whether prevention of remodeling would translate into a more stable electrophysiological profile, the investigators randomized 56 patients to treatment with angiotensin-converting enzyme (ACE) inhibition or placebo for 3 months after myocardial infarction. Programmed electrical stimulation revealed no significant differences in inducibility of monomorphic sustained ventricular tachycardia (VT), whereas ventricular fibrillation (VF) tended to be lower in the ACE-inhibitor group. Effective refractory periods were consistently longer, and dispersion of refractoriness was significantly shorter in the ACE-inhibitor group. The investigators conclude that in this small patient group ACE inhibition may mildly add to a more stable electrophysiological profile.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1071-9164
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
77-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10908079-Action Potentials,
pubmed-meshheading:10908079-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:10908079-Cardiac Pacing, Artificial,
pubmed-meshheading:10908079-Double-Blind Method,
pubmed-meshheading:10908079-Electrocardiography,
pubmed-meshheading:10908079-Humans,
pubmed-meshheading:10908079-Myocardial Infarction,
pubmed-meshheading:10908079-Perindopril,
pubmed-meshheading:10908079-Stroke Volume,
pubmed-meshheading:10908079-Ventricular Dysfunction, Left,
pubmed-meshheading:10908079-Ventricular Remodeling
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pubmed:year |
2000
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pubmed:articleTitle |
Electrophysiological changes of angiotensin-converting enzyme inhibition after myocardial infarction.
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pubmed:affiliation |
Thoraxcenter, Department of Cardiology, University Hospital Groningen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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