Source:http://linkedlifedata.com/resource/pubmed/id/10903237
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2000-9-13
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pubmed:abstractText |
A longitudinal cohort study of older adults with chronic obstructive pulmonary disease (COPD) who were stratified by FEV(1) at enrollment was done to define the etiology, frequency, severity, and medical-care impact of respiratory tract viral infections (RTVIs). Controls consisted of a group of subjects of comparable age with the patients. RTVIs were documented in 44% of observed acute respiratory illnesses in control subjects and in 27% of COPD subjects, who were followed for mean periods of 35 and 26 mo, respectively. In this heavily influenza-vaccinated cohort ( approximately 90% vaccinated each year), picornaviruses, parainfluenza viruses, and coronaviruses were most commonly identified. Mean time to return to clinical baseline was approximately 2 wk in each group. Control and COPD subjects with mild airways obstruction (baseline FEV(1) >/= 50% predicted) had few emergency-center visits or hospitalizations. Approximately half of COPD subjects with moderate/severe COPD (baseline FEV(1) < 50% predicted) had at least one emergency-center visit and/or hospitalization for acute respiratory illness. RTVIs were documented in 23% of hospitalizations and in 45% of patients admitted between December and March. RTVIs have a major impact on utilization of health care resources for COPD patients with moderate/severe airways obstruction.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1073-449X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
162
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
167-73
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10903237-Aged,
pubmed-meshheading:10903237-Female,
pubmed-meshheading:10903237-Hospitalization,
pubmed-meshheading:10903237-Humans,
pubmed-meshheading:10903237-Influenza Vaccines,
pubmed-meshheading:10903237-Longitudinal Studies,
pubmed-meshheading:10903237-Lung Diseases, Obstructive,
pubmed-meshheading:10903237-Male,
pubmed-meshheading:10903237-Middle Aged,
pubmed-meshheading:10903237-Respiratory Tract Diseases,
pubmed-meshheading:10903237-Time Factors,
pubmed-meshheading:10903237-Virus Diseases
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pubmed:year |
2000
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pubmed:articleTitle |
Respiratory viral infections in adults with and without chronic obstructive pulmonary disease.
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pubmed:affiliation |
Departments of Medicine and Microbiology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA. stepheng@bcm.tmc.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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