Source:http://linkedlifedata.com/resource/pubmed/id/10902925
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2000-11-24
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pubmed:databankReference | |
pubmed:abstractText |
The cDNAs encoding canine and feline flt3 ligand (FL) have been isolated from libraries constructed from canine or feline peripheral blood mononuclear cells and sequenced. A full-length canine FL cDNA encodes a polypeptide of 294 amino acids that shares 52.8% and 71.0% identity with the mouse and human FL protein, respectively. While the feline FL cDNA encodes a polypeptide of 291 amino acids that shares 54.1% and 70.2% identity with the mouse and human FL protein, respectively. The canine and feline FL proteins share 82.8% identity at amino acid level. Besides those encoding the full-length FL protein, several alternatively spliced forms of canine FL transcripts were also isolated. The canine and feline FL proteins have longer cytoplasmic domain than their mouse and human homologue.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1042-5179
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
163-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10902925-Alternative Splicing,
pubmed-meshheading:10902925-Amino Acid Sequence,
pubmed-meshheading:10902925-Animals,
pubmed-meshheading:10902925-Base Sequence,
pubmed-meshheading:10902925-Binding Sites,
pubmed-meshheading:10902925-Cats,
pubmed-meshheading:10902925-Cloning, Molecular,
pubmed-meshheading:10902925-Cytoplasm,
pubmed-meshheading:10902925-DNA, Complementary,
pubmed-meshheading:10902925-Dogs,
pubmed-meshheading:10902925-Humans,
pubmed-meshheading:10902925-Membrane Proteins,
pubmed-meshheading:10902925-Mice,
pubmed-meshheading:10902925-Molecular Sequence Data,
pubmed-meshheading:10902925-Protein Structure, Tertiary,
pubmed-meshheading:10902925-Sequence Homology, Amino Acid
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pubmed:year |
2000
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pubmed:articleTitle |
Molecular cloning of canine and feline flt3 ligand reveals high degree of similarity to the human and mouse homologue but uniquely long cytoplasmic domain.
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pubmed:affiliation |
Heska Corporation, Fort Collins, CO 80525, USA. shumin.yang@maxygen.com
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pubmed:publicationType |
Journal Article
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