Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2000-11-24
pubmed:databankReference
pubmed:abstractText
The cDNAs encoding canine and feline flt3 ligand (FL) have been isolated from libraries constructed from canine or feline peripheral blood mononuclear cells and sequenced. A full-length canine FL cDNA encodes a polypeptide of 294 amino acids that shares 52.8% and 71.0% identity with the mouse and human FL protein, respectively. While the feline FL cDNA encodes a polypeptide of 291 amino acids that shares 54.1% and 70.2% identity with the mouse and human FL protein, respectively. The canine and feline FL proteins share 82.8% identity at amino acid level. Besides those encoding the full-length FL protein, several alternatively spliced forms of canine FL transcripts were also isolated. The canine and feline FL proteins have longer cytoplasmic domain than their mouse and human homologue.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1042-5179
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
163-6
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Molecular cloning of canine and feline flt3 ligand reveals high degree of similarity to the human and mouse homologue but uniquely long cytoplasmic domain.
pubmed:affiliation
Heska Corporation, Fort Collins, CO 80525, USA. shumin.yang@maxygen.com
pubmed:publicationType
Journal Article