Linked Life Data

10901922

Source:http://linkedlifedata.com/resource/pubmed/id/10901922

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-8-10
pubmed:abstractText
More than 10% of retroperitoneal paragangliomas are malignant. Histopathological appearance is unreliable in distinguishing benign from malignant paragangliomas. In this study the computed tomography (CT) features of retroperitoneal paragangliomas were analysed to determine if benign neoplasms could be distinguished from malignancy by their appearance at imaging. We reviewed the clinical profiles and CT scans of 27 benign and seven malignant retroperitoneal paragangliomas in 32 patients to determine the presence of any characteristic appearances of benign and malignant neoplasms. Extra-adrenal paragangliomas were more frequently malignant (50%) than adrenal neoplasms (12.5%). Benign lesions were generally smaller (average 6.1 cm) than malignant lesions (average 7.9 cm). Benign tumours were more likely to be homogeneous (46.2%) and have well-defined margins (92.3%) than malignant tumours (25 and 12.5% respectively). Larger tumours were more frequently necrotic. Malignant retroperitoneal paragangliomas infiltrated adjacent liver, pancreas, bowel, lymph nodes, blood vessels, or metastasized to bone and liver. Malignant retroperitoneal paragangliomas are frequently extra-adrenal, large and heterogeneous, with ill-defined margin and necrosis. CT is useful for delineating the location, extent and nature of these tumours. Infiltration of surrounding tissues or organs, metastases, and resectability are accurately assessed by CT.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0004-8461
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
303-6
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Computed tomography of retroperitoneal paragangliomas.
pubmed:affiliation
Department of Radiology, First Affiliated Hospital of Sun Yat-Sen University of Medical Sciences, Guangzhou, China. m-pui@cyber.net.pk
pubmed:publicationType
Journal Article, Comparative Study