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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2000-8-24
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pubmed:abstractText |
Neutrophils are the main inflammatory cell present in lesions involving the central nervous system (CNS) during human and murine listeriosis. In this study, administration of the neutrophil-depleting monoclonal antibody RB6-8C5 during experimental murine listeriosis facilitated the multiplication of Listeria monocytogenes in the CNS. These data suggest that neutrophils play a key role in eliminating bacteria that gain access to the CNS compartment. In addition, we provide evidence that their migration into the CNS may be necessary for the subsequent recruitment of macrophages and activated lymphocytes.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-10377133,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-10405304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-10514421,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-1425736,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-14467923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-1943998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-6618532,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-7476097,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-7591057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-7790763,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-7835951,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-7927800,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-8225586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-8270870,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-8751957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-8805652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-9009323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10899890-9815218
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4789-91
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10899890-Animals,
pubmed-meshheading:10899890-Antibodies, Monoclonal,
pubmed-meshheading:10899890-Bacteremia,
pubmed-meshheading:10899890-Central Nervous System Infections,
pubmed-meshheading:10899890-Female,
pubmed-meshheading:10899890-Listeriosis,
pubmed-meshheading:10899890-Liver,
pubmed-meshheading:10899890-Mice,
pubmed-meshheading:10899890-Neutrophils,
pubmed-meshheading:10899890-Spleen
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pubmed:year |
2000
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pubmed:articleTitle |
Critical role of neutrophils in eliminating Listeria monocytogenes from the central nervous system during experimental murine listeriosis.
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pubmed:affiliation |
Department of Pathology and Animal Productions, Veterinary School, Autonomous University of Barcelona, Barcelona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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