Linked Life Data

10898355

Source:http://linkedlifedata.com/resource/pubmed/id/10898355

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12 Suppl
pubmed:dateCreated
2000-7-27
pubmed:abstractText
Bisphosphonates have been used successfully for many years in the treatment of hypercalcemia and to reduce skeletal-related complications of metastases. In the first years of bisphosphonate use, the efficacy of these substances was thought to lie purely in the inhibition of osteoclasts. However, there is recent evidence to suggest that an antitumor effect also may play a role. As well as having an apoptotic and antiproliferative effect on osteoclasts, bisphosphonates may exert a similar influence on macrophages and tumor cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0008-543X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
88
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3080-8
pubmed:dateRevised
2006-3-8
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Bisphosphonates and the prevention of metastasis: first evidences from preclinical and clinical studies.
pubmed:affiliation
Department of Obstetrics and Gynecology, University Hospital, Heidelberg, Germany. ingo_diel@med.uni-heidelberg.de
pubmed:publicationType
Journal Article, Review