Linked Life Data

10897863

Source:http://linkedlifedata.com/resource/pubmed/id/10897863

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-7-31
pubmed:abstractText
Six rats were trained to make an operant response to receive brief trains of electrical current to the lateral hypothalamus (self-stimulation). All animals were then randomly exposed to pressures of 4.03, 5.51, 7.06, or 10.1 ATA breathing either compressed air or N2-O2 and 13.1 ATA (N2-O2 only). When the subjects breathed air at pressures of 7.06 and 10.1 ATA, rate of self-stimulation decreased by 32 and 43%, respectively. No differences were observed in rate of response at any pressure when the animals breathed N2-O2 with the partial pressure of oxygen maintained at 0.2 ATA. When an oxygen-nitrogen mixture was breathed at 3 ATA in which the PO2 was similar to compressed air at 10.1 ATA, self-stimulation rate was decreased by 40%; this suggests that PO2 is a critical variable influencing behavior mediated by brain stimulation. Results are discussed in terms of the use of self-stimulation as one tool for better understanding the neuronal mechanisms of behavior as they relate to breathing-gas mixtures at increased pressures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0093-5387
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
369-78
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Brain stimulation in rats exposed to hyperbaric environments.
pubmed:affiliation
Behavioral Sciences Department, U.S. Naval Medical Research Institute, Bethesda, MD 20014, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.