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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2000-7-27
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pubmed:abstractText |
Neuronal migration disorders (NMD) are often associated with therapy-resistant epilepsy. In human cerebral cortex, this hyperexcitability has been correlated with a loss of inhibitory interneurons. We used a rat model of focal cortical NMD (microgyria) to determine whether the expression of epileptiform activity in this model coincides with a decrease in inhibitory interneurons.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0013-9580
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
781-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10897147-Adult,
pubmed-meshheading:10897147-Animals,
pubmed-meshheading:10897147-Animals, Newborn,
pubmed-meshheading:10897147-Calcium-Binding Protein, Vitamin D-Dependent,
pubmed-meshheading:10897147-Cell Count,
pubmed-meshheading:10897147-Disease Models, Animal,
pubmed-meshheading:10897147-Epilepsy,
pubmed-meshheading:10897147-Freezing,
pubmed-meshheading:10897147-Frontal Lobe,
pubmed-meshheading:10897147-Humans,
pubmed-meshheading:10897147-Immunohistochemistry,
pubmed-meshheading:10897147-Interneurons,
pubmed-meshheading:10897147-Neocortex,
pubmed-meshheading:10897147-Neural Inhibition,
pubmed-meshheading:10897147-Neural Tube Defects,
pubmed-meshheading:10897147-Parietal Lobe,
pubmed-meshheading:10897147-Parvalbumins,
pubmed-meshheading:10897147-Pyramidal Cells,
pubmed-meshheading:10897147-Rats,
pubmed-meshheading:10897147-Rats, Wistar,
pubmed-meshheading:10897147-Receptors, GABA,
pubmed-meshheading:10897147-gamma-Aminobutyric Acid
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pubmed:year |
2000
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pubmed:articleTitle |
Characterization of neuronal migration disorders in neocortical structures: loss or preservation of inhibitory interneurons?
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pubmed:affiliation |
Institute of Neurophysiology, University of Düsseldorf, Düsseldorf, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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