Source:http://linkedlifedata.com/resource/pubmed/id/10897015
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2000-8-2
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pubmed:abstractText |
Successful chemotherapy for patients with soft tissue sarcoma (STS) has been limited by a lack of active drugs. The most effective single agents are doxorubicin, dacarbazine, and, more recently, ifosfamide. Previously the most widely used combination has been CYVADIC (cyclophosphamide, vincristine, doxorubicin, and dacarbazine). In one randomized trial, ifosfamide was superior to cyclophosphamide; two nonrandomized studies also reported favorable results. Etoposide monotherapy was successful in 8%; the effectiveness of cisplatin was 5-23%. In view of these findings, the authors treated STS patients with an etoposide, cisplatin, and ifosfamide (VIP) combination.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2000 American Cancer Society.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
177-80
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:10897015-Adult,
pubmed-meshheading:10897015-Aged,
pubmed-meshheading:10897015-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:10897015-Cisplatin,
pubmed-meshheading:10897015-Drug Administration Schedule,
pubmed-meshheading:10897015-Etoposide,
pubmed-meshheading:10897015-Female,
pubmed-meshheading:10897015-Humans,
pubmed-meshheading:10897015-Ifosfamide,
pubmed-meshheading:10897015-Infusions, Intravenous,
pubmed-meshheading:10897015-Male,
pubmed-meshheading:10897015-Middle Aged,
pubmed-meshheading:10897015-Sarcoma,
pubmed-meshheading:10897015-Soft Tissue Neoplasms,
pubmed-meshheading:10897015-Treatment Outcome
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pubmed:year |
2000
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pubmed:articleTitle |
The efficacy of a combination of etoposide, ifosfamide, and cisplatin in the treatment of patients with soft tissue sarcoma.
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pubmed:affiliation |
Department of Chemotherapy, National Institute of Oncology, Budapest, Hungary.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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