| pubmed-article:10896894 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C0037929 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C0037925 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C0005682 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C0596588 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C0205217 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:10896894 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:10896894 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10896894 | pubmed:dateCreated | 2000-9-27 | lld:pubmed |
| pubmed-article:10896894 | pubmed:abstractText | These studies examined Fos protein expression in spinal cord neurons synaptically activated by stimulation of bladder afferent pathways after spinal cord injury (SCI). In urethan-anesthetized Wistar rats after SCI for 6 wk, intravesical saline distension significantly (P </= 0.005) increased the number of Fos-immunoreactive (IR) cells in the rostrolumbar (L1, 38 cells/section; L2, 29 cells/section) and caudal lumbosacral (L6, 140 cells/section; S1, 110 cells/section) spinal cord compared with control animals, but Fos expression in the L5 segment was not altered. The distribution of Fos-IR cells was also altered in the lumbosacral spinal cord. Significantly greater numbers of Fos-IR cells were distributed in the dorsal commissure and medial and lateral dorsal horn after intravesical distension in SCI animals. Large percentages of parasympathetic (75%) and sympathetic (85%) preganglionic neurons also expressed Fos-IR after intravesical distension in SCI animals. These results demonstrate that bladder distension produces increased numbers and an altered distribution pattern of Fos-IR cells after SCI. This pattern resembles that after noxious irritation of the bladder in control animals. Pretreatment with capsaicin significantly reduced the number of Fos-IR cells induced by bladder distension after SCI. These data suggest that SCI can reveal an altered Fos expression pattern in response to a nonnoxious bladder stimulus that is partially mediated by capsaicin-sensitive bladder afferents. | lld:pubmed |
| pubmed-article:10896894 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10896894 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10896894 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10896894 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10896894 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10896894 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10896894 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:10896894 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10896894 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10896894 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:10896894 | pubmed:issn | 0363-6119 | lld:pubmed |
| pubmed-article:10896894 | pubmed:author | pubmed-author:VizzardM AMA | lld:pubmed |
| pubmed-article:10896894 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10896894 | pubmed:volume | 279 | lld:pubmed |
| pubmed-article:10896894 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10896894 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10896894 | pubmed:pagination | R295-305 | lld:pubmed |
| pubmed-article:10896894 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:10896894 | pubmed:meshHeading | pubmed-meshheading:10896894... | lld:pubmed |
| pubmed-article:10896894 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10896894 | pubmed:articleTitle | Increased expression of spinal cord Fos protein induced by bladder stimulation after spinal cord injury. | lld:pubmed |
| pubmed-article:10896894 | pubmed:affiliation | University of Vermont College of Medicine, Departments of Neurology and Anatomy and Neurobiology, Burlington, Vermont 05405, USA. mvizzard@zoo.uvm.edu | lld:pubmed |
| pubmed-article:10896894 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10896894 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10896894 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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