Source:http://linkedlifedata.com/resource/pubmed/id/10896829
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-8-17
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pubmed:abstractText |
We have recently proposed that the "distal esophagus" in esophageal atresia with tracheo-esophageal fistula (EA/TEF) is actually embryologically derived from the middle branch of a trifurcation of the embryonic lung bud, which subsequently grows caudally in the foregut to connect with the developing stomach. We hypothesized that differential mRNA expression of the lung-specific patterning transcription factor, thyroid transcription factor 1 (TTF-1), in the developing fistula tract in TEF relative to the bronchi (the other branches of the lung bud trifurcation) might explain the unique nonbranching pattern of growth of the fistula tract.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-4804
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2000 Academic Press.
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pubmed:issnType |
Print
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pubmed:volume |
92
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
245-9
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:10896829-Animals,
pubmed-meshheading:10896829-Doxorubicin,
pubmed-meshheading:10896829-Epithelium,
pubmed-meshheading:10896829-Esophageal Atresia,
pubmed-meshheading:10896829-Esophagus,
pubmed-meshheading:10896829-Female,
pubmed-meshheading:10896829-Gene Expression Regulation, Developmental,
pubmed-meshheading:10896829-In Situ Hybridization,
pubmed-meshheading:10896829-Lung,
pubmed-meshheading:10896829-Nuclear Proteins,
pubmed-meshheading:10896829-Pregnancy,
pubmed-meshheading:10896829-Rats,
pubmed-meshheading:10896829-Rats, Sprague-Dawley,
pubmed-meshheading:10896829-Thyroid Gland,
pubmed-meshheading:10896829-Trachea,
pubmed-meshheading:10896829-Tracheoesophageal Fistula,
pubmed-meshheading:10896829-Transcription Factors
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pubmed:year |
2000
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pubmed:articleTitle |
Patterning of the "distal esophagus" in esophageal atresia with tracheo-esophageal fistula: is thyroid transcription factor 1 a player?
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pubmed:affiliation |
Laboratory of Developmental Biology and Repair, New York University Medical Center, New York, New York, 10016, USA.
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pubmed:publicationType |
Journal Article
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