Source:http://linkedlifedata.com/resource/pubmed/id/10893848
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-8-11
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pubmed:abstractText |
To determine whether fasting glucose/insulin (FG/I) ratio and insulin levels 2 h after 75-g oral load of glucose (IL-2 h PG) are predictors for type 2 diabetes mellitus, a comparative 2 year follow-up study was conducted. Ninety-six healthy subjects 30 years of age or older, randomly selected from the general population of Durango, Mexico were included in two groups: 1) risk group: members had both baseline FG/I ratio and IL 2-h PG within the lower and upper quartile, respectively, and 2) control group, whose members had baseline FG/I ratio and IL 2-h PG within the second and third quartiles, respectively. Multivariate logistic regression was used to compute the relative risk for the development of type 2 diabetes. The family history of diabetes (RR 10.1; IC95% 2.7-15.8, p < 0.01), glucose intolerance (RR 9.8; IC95% 1.7-13.4, p < 0.01), abdominal obesity (RR 6.1; IC95% 1.5-10.1, p < 0.01), and the low FG/I ratio and high IL 2-h PG (RR 3.3; IC95% 1.4-8.2, p < 0.05) were strong predictors for type 2 diabetes. Critical values for predicting criteria of FG/I ratio and IL 2-h PG were of 4.0 y 180 microUI/ml, respectively. In conclusion, the measurement of FG/I ratio and IL 2-h PG is an accurate indicator for estimating the risk of developing type 2 diabetes.
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pubmed:language |
spa
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0016-3813
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
201-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10893848-Adult,
pubmed-meshheading:10893848-Blood Glucose,
pubmed-meshheading:10893848-Diabetes Mellitus, Type 2,
pubmed-meshheading:10893848-Fasting,
pubmed-meshheading:10893848-Female,
pubmed-meshheading:10893848-Glucose,
pubmed-meshheading:10893848-Humans,
pubmed-meshheading:10893848-Insulin,
pubmed-meshheading:10893848-Male,
pubmed-meshheading:10893848-Predictive Value of Tests,
pubmed-meshheading:10893848-Prospective Studies
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pubmed:articleTitle |
[Fasting glucose/insulin index and insulin levels 2-h after glucose load are predictors of the development of type 2 diabetes].
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pubmed:affiliation |
Hospital Regional, Instituto Mexicano del Seguro Social Delegación Durango, Mex.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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