Source:http://linkedlifedata.com/resource/pubmed/id/10891795
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6-7
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pubmed:dateCreated |
2000-10-19
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pubmed:abstractText |
Creutzfeldt-Jakob disease (CJD) is the most frequent human spongiform encephalopathy. We have analyzed 53 cases of definite non familial CJD over a study period of 28 years. All were autopsied in the same neuropathological unit. Clinical and epidemiological data were in accordance with previous studies: low incidence of CJD under the age of 40, high incidence around the sixty years of age (26%) a sex ratio at 0.65 and high frequency of myoclonus, dementia and cerebellar ataxia during evolution (78%). This study highlights the rapidity at the onset of the disease (within 24 hours) in 16% of the cases. EEG disclosed typical pseudoperiodic activity in only 53% of cases and cerebral MRI showed high T2 signal intensity in basal nuclei in 15%. This regional study is the second of its nature to be carried out in France, the first one covering the area of Paris.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0035-3787
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
156
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
616-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10891795-Adult,
pubmed-meshheading:10891795-Brain,
pubmed-meshheading:10891795-Creutzfeldt-Jakob Syndrome,
pubmed-meshheading:10891795-Electroencephalography,
pubmed-meshheading:10891795-Female,
pubmed-meshheading:10891795-France,
pubmed-meshheading:10891795-Humans,
pubmed-meshheading:10891795-Incidence,
pubmed-meshheading:10891795-Magnetic Resonance Imaging,
pubmed-meshheading:10891795-Male,
pubmed-meshheading:10891795-Middle Aged,
pubmed-meshheading:10891795-Retrospective Studies,
pubmed-meshheading:10891795-Risk Factors
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pubmed:year |
2000
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pubmed:articleTitle |
[Non-familial Creutzfeldt-Jakob disease: a study of 53 cases].
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pubmed:affiliation |
Service de Neurologie D, Hôpital Neurologique Pierre Wertheimer, Lyon. glap@wanadoo.fr
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pubmed:publicationType |
Journal Article,
English Abstract,
Review
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