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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2000-8-3
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pubmed:abstractText |
In portal hypertension, the mechanisms responsible for nitric oxide (NO) overproduction and vasodilation have not yet been clearly identified. One hypothesis is that NO synthase (NOS) 3 is overactivated because of shear stress in endothelial cells caused by hyperkinetic circulation. The aim of this study was to evaluate aortic NOS3 after a reduction of blood flow by long-time beta-adrenoceptor antagonist administration.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenergic beta-Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Antihypertensive Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Atenolol,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/Nos3 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Propranolol,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Vasodilator Agents
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
119
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
196-200
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10889169-Adrenergic beta-Antagonists,
pubmed-meshheading:10889169-Animals,
pubmed-meshheading:10889169-Antihypertensive Agents,
pubmed-meshheading:10889169-Aorta,
pubmed-meshheading:10889169-Atenolol,
pubmed-meshheading:10889169-Constriction, Pathologic,
pubmed-meshheading:10889169-Hypertension, Portal,
pubmed-meshheading:10889169-Male,
pubmed-meshheading:10889169-Nitric Oxide Synthase,
pubmed-meshheading:10889169-Nitric Oxide Synthase Type III,
pubmed-meshheading:10889169-Portal Vein,
pubmed-meshheading:10889169-Propranolol,
pubmed-meshheading:10889169-RNA, Messenger,
pubmed-meshheading:10889169-Rats,
pubmed-meshheading:10889169-Rats, Sprague-Dawley,
pubmed-meshheading:10889169-Reference Values,
pubmed-meshheading:10889169-Vasodilation,
pubmed-meshheading:10889169-Vasodilator Agents
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pubmed:year |
2000
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pubmed:articleTitle |
Role of aortic nitric oxide synthase 3 (eNOS) in the systemic vasodilation of portal hypertension.
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pubmed:affiliation |
Laboratoire d'Hémodynamique Splanchnique et de Biologie Vasculaire, INSERM Unité 481, Hôpital Beaujon, Clichy, France.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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