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rdf:type |
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lifeskim:mentions |
umls-concept:C0007585,
umls-concept:C0010592,
umls-concept:C0014257,
umls-concept:C0016030,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0221908,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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|
pubmed:issue |
1
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pubmed:dateCreated |
2000-8-21
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pubmed:abstractText |
Nephrotoxicity, accelerated atherosclerosis, and graft vascular disease are common complications of cyclosporine long-term treatment characterized by a wide disruption of organ architecture with increased interstitial areas and accumulation of extracellular matrix (ECM). How cyclosporine induces these changes is not clear, but it is conceivable that they are the sum of changes induced at the cell level.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
123-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10886556-Actins,
pubmed-meshheading:10886556-Capillaries,
pubmed-meshheading:10886556-Cell Division,
pubmed-meshheading:10886556-Cells, Cultured,
pubmed-meshheading:10886556-Collagen,
pubmed-meshheading:10886556-Cyclosporine,
pubmed-meshheading:10886556-Endothelium, Vascular,
pubmed-meshheading:10886556-Epithelial Cells,
pubmed-meshheading:10886556-Extracellular Matrix Proteins,
pubmed-meshheading:10886556-Fibroblasts,
pubmed-meshheading:10886556-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:10886556-Humans,
pubmed-meshheading:10886556-Immunosuppressive Agents,
pubmed-meshheading:10886556-Kidney Transplantation,
pubmed-meshheading:10886556-Kidney Tubules,
pubmed-meshheading:10886556-Matrix Metalloproteinase 9,
pubmed-meshheading:10886556-Nitric Oxide,
pubmed-meshheading:10886556-RNA, Messenger,
pubmed-meshheading:10886556-Skin,
pubmed-meshheading:10886556-Tissue Inhibitor of Metalloproteinase-1
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pubmed:year |
2000
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pubmed:articleTitle |
Cyclosporine induces different responses in human epithelial, endothelial and fibroblast cell cultures.
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pubmed:affiliation |
Division of Nephrology and Dialysis, IRCCS Policlinico San Matteo, University of Pavia, Italy. ciroe@pop.systemy.it
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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