|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0000768,
umls-concept:C0040648,
umls-concept:C0242303,
umls-concept:C0332453,
umls-concept:C0410528,
umls-concept:C0450199,
umls-concept:C0599894,
umls-concept:C0600031,
umls-concept:C1274040,
umls-concept:C1412734,
umls-concept:C1521840
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|
pubmed:issue |
6
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|
pubmed:dateCreated |
2000-9-6
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|
pubmed:abstractText |
NK homeobox genes have been shown to play important roles in cell-type specification and organogenesis. Murine Bapx1, a member of NK homeobox gene family, is expressed in all the cartilageous tissues that undergo endochondral bone formation, and in gut mesentery during embryogenesis, suggesting that Bapx1 may be a key transcription factor ragulating the development of these organs.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
1356-9597
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
5
|
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
499-513
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pubmed:dateRevised |
2011-10-26
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pubmed:meshHeading |
pubmed-meshheading:10886375-Abnormalities, Multiple,
pubmed-meshheading:10886375-Animals,
pubmed-meshheading:10886375-Animals, Newborn,
pubmed-meshheading:10886375-Bone Diseases, Developmental,
pubmed-meshheading:10886375-Cell Division,
pubmed-meshheading:10886375-Digestive System,
pubmed-meshheading:10886375-Digestive System Abnormalities,
pubmed-meshheading:10886375-Gene Expression,
pubmed-meshheading:10886375-Gene Targeting,
pubmed-meshheading:10886375-Homeodomain Proteins,
pubmed-meshheading:10886375-Mice,
pubmed-meshheading:10886375-Mice, Knockout,
pubmed-meshheading:10886375-Organ Specificity,
pubmed-meshheading:10886375-Spine,
pubmed-meshheading:10886375-Spleen,
pubmed-meshheading:10886375-Transcription Factors
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|
pubmed:year |
2000
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|
pubmed:articleTitle |
Targeted disruption of the homeobox transcription factor Bapx1 results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation.
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pubmed:affiliation |
Department of Cell Biology, The Cancer Institute, Japanese Foundation for Cancer Research, 1-37-1 Kami-ikebukuro, Toshima-ku, Tokyo 170-8455, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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