Linked Life Data

10886373

Source:http://linkedlifedata.com/resource/pubmed/id/10886373

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2000-9-6
pubmed:abstractText
The c-myc oncogene product (c-Myc) is a transcription factor that forms a complex with Max and recognizes the E-box sequence. c-Myc plays key functions in cell proliferation, differentiation and apoptosis. As for its activity towards cell proliferation, it is generally thought that c-Myc transactivates the E-box-containing genes that encode proteins essential to cell-cycle progression. Despite the characterization of candidate genes regulated by c-Myc in culture cells, these have still not been firmly recognized as real target genes for c-Myc.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1356-9597
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
481-90
pubmed:dateRevised
2011-10-27
pubmed:meshHeading
pubmed-meshheading:10886373-Binding, Competitive, pubmed-meshheading:10886373-Chromosomal Proteins, Non-Histone, pubmed-meshheading:10886373-DNA-Binding Proteins, pubmed-meshheading:10886373-Dose-Response Relationship, Drug, pubmed-meshheading:10886373-Electrophoresis, Polyacrylamide Gel, pubmed-meshheading:10886373-Genes, Reporter, pubmed-meshheading:10886373-HeLa Cells, pubmed-meshheading:10886373-Humans, pubmed-meshheading:10886373-Macromolecular Substances, pubmed-meshheading:10886373-Origin Recognition Complex, pubmed-meshheading:10886373-Peptide Fragments, pubmed-meshheading:10886373-Proto-Oncogene Proteins c-myc, pubmed-meshheading:10886373-Recombinant Fusion Proteins, pubmed-meshheading:10886373-Transcription, Genetic, pubmed-meshheading:10886373-Transcription Factors, pubmed-meshheading:10886373-Transfection
pubmed:year
2000
pubmed:articleTitle
ORC1 interacts with c-Myc to inhibit E-box-dependent transcription by abrogating c-Myc-SNF5/INI1 interaction.
pubmed:affiliation
Graduate School of Pharmaceutical Sciences; College of Medical Technology, Hokkaido University, Kita-ku, Sapporo 060, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't