Linked Life Data

10885572

Source:http://linkedlifedata.com/resource/pubmed/id/10885572

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2000-11-7
pubmed:databankReference
pubmed:abstractText
The HLA-DM genes (DMA and DMB) are encoded in the major histocompatibility complex (MHC) on human chromosome 6. They are involved in the loading of antigenic peptide onto class II molecules as part of the class II antigen-processing and -presentation pathway. During a study of Oriental subjects (11 Chinese and 26 Japanese subjects), one Chinese subject was identified as having a new DMB allele using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). This was confirmed with sequencing. The new allele was found to have Glu (GAG) and Thr (ACT) at positions 144 and 179 respectively. This was a previously unpublished combination of polymorphic sites, and was submitted to GenBank and assigned the accession number AF072680, and named HLA-DMB*0106.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0001-2815
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
470-2
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
The nucleotide sequence of a new DMB allele, DMB*0106.
pubmed:affiliation
Department of Medicine, Birmingham University, United Kingdom. C.L.Perry@bham.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't