Linked Life Data

10884934

Source:http://linkedlifedata.com/resource/pubmed/id/10884934

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2000-10-18
pubmed:abstractText
The stratum corneum is a complex biological material characterized by very low permeability to water and most other molecules. This material may be thought of as a 'porous medium' composed of impermeable and permeable regions. Intercellular lipid membranes in the stratum corneum are postulated to exist in a mixture of two phases: solid (i.e. impermeable) and liquid crystalline (permeable). The corneocyte envelope is classified as impermeable. Diffusion mechanisms of solutes within, across and between the intercellular lamellae are discussed. This model represents a refinement of previous theories about the physical structures responsible for the low observed permeability of the stratum corneum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0365-8341
pubmed:author
pubmed:issnType
Print
pubmed:volume
208
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
12-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Hypothesis: the epidermal permeability barrier is a porous medium.
pubmed:affiliation
Dept. of Medicine, University of British Columbia, Vancouver, Canada. nkitson@interchange.ubc.ca
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't