| pubmed-article:10884527 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C1304649 | lld:lifeskim |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C0999699 | lld:lifeskim |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C0037659 | lld:lifeskim |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C1515999 | lld:lifeskim |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C0205373 | lld:lifeskim |
| pubmed-article:10884527 | lifeskim:mentions | umls-concept:C0445254 | lld:lifeskim |
| pubmed-article:10884527 | pubmed:issue | 2-3 | lld:pubmed |
| pubmed-article:10884527 | pubmed:dateCreated | 2000-9-22 | lld:pubmed |
| pubmed-article:10884527 | pubmed:abstractText | The systemic anti-inflammatory effect induced by antidromic sensory nerve stimulation was investigated in rats and guinea-pigs. In atropine-pretreated rats, bilateral antidromic stimulation of vagal afferent fibres (8 Hz, 20 min, at C-fibre strength) inhibited plasma extravasation induced by 1% mustard oil on the acutely denervated hindlegs by 36.45+/-3.95%. Both the prevention of this inhibitory effect by cysteamine pretreatment and the stimulation-evoked rise of plasma somatostatin-like immunoreactivity in the two species suggest a mediator role of neural somatostatin. Since this response was blocked by systemic capsaicin pretreatment and slightly reduced after subdiaphragmal vagotomy, participation of thoracic capsaicin-sensitive afferents is indicated. In guinea-pigs pretreated with guanethidine and pipecuronium, antidromic sciatic nerve stimulation induced 45.46+/-5.08% inhibition on the contralateral leg and increased plasma somatostatin-like immunoreactivity. It is concluded that somatostatin released from the activated vagal capsaicin-sensitive sensory nerve terminals of the rat and somatic nerves of the guinea-pigs exerts a systemic humoral function. | lld:pubmed |
| pubmed-article:10884527 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10884527 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10884527 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10884527 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10884527 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:10884527 | pubmed:issn | 0014-2999 | lld:pubmed |
| pubmed-article:10884527 | pubmed:author | pubmed-author:SzolcsányiJJ | lld:pubmed |
| pubmed-article:10884527 | pubmed:author | pubmed-author:PintérEE | lld:pubmed |
| pubmed-article:10884527 | pubmed:author | pubmed-author:NémethJJ | lld:pubmed |
| pubmed-article:10884527 | pubmed:author | pubmed-author:SzilvássyZZ | lld:pubmed |
| pubmed-article:10884527 | pubmed:author | pubmed-author:HelyesZZ | lld:pubmed |
| pubmed-article:10884527 | pubmed:author | pubmed-author:ThánMM | lld:pubmed |
| pubmed-article:10884527 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10884527 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:10884527 | pubmed:volume | 399 | lld:pubmed |
| pubmed-article:10884527 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10884527 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10884527 | pubmed:pagination | 251-8 | lld:pubmed |
| pubmed-article:10884527 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:10884527 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10884527 | pubmed:articleTitle | Systemic anti-inflammatory effect of somatostatin released from capsaicin-sensitive vagal and sciatic sensory fibres of the rat and guinea-pig. | lld:pubmed |
| pubmed-article:10884527 | pubmed:affiliation | Department of Pharmacology and Pharmacotherapy, University Medical School of Pécs, H-7601 P.O.Box 99, Pécs, Hungary. | lld:pubmed |
| pubmed-article:10884527 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10884527 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
