|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0022116,
umls-concept:C0034693,
umls-concept:C0079883,
umls-concept:C0175677,
umls-concept:C0205234,
umls-concept:C0205374,
umls-concept:C0228174,
umls-concept:C0231491,
umls-concept:C0475224,
umls-concept:C0556636,
umls-concept:C0682708,
umls-concept:C0950847
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|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2000-8-2
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|
pubmed:abstractText |
Cerebral white matter is as sensitive as gray matter to ischemic injury and is probably amenable to pharmacological intervention. In this study we investigated whether an N-methyl-D-aspartate (NMDA) antagonist, CNS 1102, protects not only cerebral gray matter but also white matter from ischemic injury.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0039-2499
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
31
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1709-14
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:10884477-Animals,
pubmed-meshheading:10884477-Cerebral Cortex,
pubmed-meshheading:10884477-Excitatory Amino Acid Antagonists,
pubmed-meshheading:10884477-Guanidines,
pubmed-meshheading:10884477-Infarction, Middle Cerebral Artery,
pubmed-meshheading:10884477-Internal Capsule,
pubmed-meshheading:10884477-Ischemic Attack, Transient,
pubmed-meshheading:10884477-Male,
pubmed-meshheading:10884477-Nerve Fibers,
pubmed-meshheading:10884477-Neurons,
pubmed-meshheading:10884477-Neuroprotective Agents,
pubmed-meshheading:10884477-Rats,
pubmed-meshheading:10884477-Rats, Sprague-Dawley,
pubmed-meshheading:10884477-Receptors, N-Methyl-D-Aspartate,
pubmed-meshheading:10884477-Reperfusion Injury
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|
pubmed:year |
2000
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|
pubmed:articleTitle |
The N-methyl-D-aspartate antagonist CNS 1102 protects cerebral gray and white matter from ischemic injury following temporary focal ischemia in rats.
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|
pubmed:affiliation |
Department of Neurology, University of Massachusetts Memorial Health Care and University of Massachusetts Medical School, Worcester, MA 01605, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
