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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2000-8-25
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pubmed:abstractText |
Microparticles released from platelets may play a role in the normal hemostatic response to vascular injury, because they exhibit prothrombinase activity. Microparticles are generated by high shear stress and may be formed in diseased small arteries and arterioles in various clinical settings. However, the surface composition of high shear-induced platelet microparticles is unknown. It was recently shown that some cytokines modulate platelet activation. However, no reports are available concerning the effect of cytokines on high shear-induced platelet aggregation (SIPA) microparticle generation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0196-4763
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2000 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
173-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10878559-Annexin A5,
pubmed-meshheading:10878559-Antibodies, Monoclonal,
pubmed-meshheading:10878559-Antigens, CD,
pubmed-meshheading:10878559-Binding Sites,
pubmed-meshheading:10878559-Blood Platelets,
pubmed-meshheading:10878559-Cytokines,
pubmed-meshheading:10878559-Erythropoietin,
pubmed-meshheading:10878559-Flow Cytometry,
pubmed-meshheading:10878559-Humans,
pubmed-meshheading:10878559-Image Cytometry,
pubmed-meshheading:10878559-Interleukin-6,
pubmed-meshheading:10878559-Microscopy, Confocal,
pubmed-meshheading:10878559-Platelet Aggregation,
pubmed-meshheading:10878559-Stress, Mechanical,
pubmed-meshheading:10878559-Subcellular Fractions,
pubmed-meshheading:10878559-Thrombopoietin
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pubmed:year |
2000
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pubmed:articleTitle |
Cytometric analysis of high shear-induced platelet microparticles and effect of cytokines on microparticle generation.
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pubmed:affiliation |
Otsuka America Pharmaceutical Inc., Rockville, Maryland, USA. fwkg4681@mb.infoweb.ne.jp
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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