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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-10-13
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pubmed:abstractText |
Leptin, the ob/ob gene product, is a recently discovered peptide hormone, secreted by adipocytes, which can act as a satiety factor to regulate food intake. Its levels thus will be related to the presence of food in the lumen of the gut, and food intake is one of the most potent stimuli for intestinal epithelial cell proliferation. Leptin has a variety of other actions and the aim of this study was to see if one of these was to stimulate mucosal growth.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0012-2823
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2000 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
223-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10878448-Animals,
pubmed-meshheading:10878448-Body Weight,
pubmed-meshheading:10878448-Cell Division,
pubmed-meshheading:10878448-Colon,
pubmed-meshheading:10878448-Epithelial Cells,
pubmed-meshheading:10878448-Injections, Intraperitoneal,
pubmed-meshheading:10878448-Intestinal Mucosa,
pubmed-meshheading:10878448-Intestine, Small,
pubmed-meshheading:10878448-Leptin,
pubmed-meshheading:10878448-Male,
pubmed-meshheading:10878448-Mice,
pubmed-meshheading:10878448-Mice, Inbred C57BL,
pubmed-meshheading:10878448-Organ Size,
pubmed-meshheading:10878448-Recombinant Proteins,
pubmed-meshheading:10878448-Starvation
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pubmed:year |
2000
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pubmed:articleTitle |
Starvation, leptin and epithelial cell proliferation in the gastrointestinal tract of the mouse.
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pubmed:affiliation |
Department of Histopathology, Division of Investigative Science, Imperial College School of Medicine, Hammersmith Hospital, London, UK.
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pubmed:publicationType |
Journal Article,
Comparative Study
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