Linked Life Data

10878253

Source:http://linkedlifedata.com/resource/pubmed/id/10878253

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2000-8-2
pubmed:abstractText
Members of the ATP-dependent class of chromatin remodeling enzymes are found in all eukaryotes where they play key roles in many DNA-mediated processes. Each of these enzymes are multi-subunit assembles that hydrolyze approximately 1000 ATP/min. The energy of ATP hydrolysis is used to disrupt the chromatin structure which can be scored by enhanced factor binding, disruption of the DNase I cleavage pattern of mononucleosomes, formation of dinucleosomes, movements of histone octamers in cis and in trans, and by generation of nuclease hypersensitive sites. Here the biochemical properties of these enzymes are reviewed and the manner in which ATP-driven nucleosome movements might account for many of these diverse activities is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
476
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
68-72
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
ATP-dependent chromatin remodeling: going mobile.
pubmed:affiliation
Program in Molecular Medicine and Department of Biochemistry and Molecular Biology, Biotech 2, Suite 301, 373 Plantation St., 01605, Worcester, MA, USA. craig.peterson@umassmed.edu
pubmed:publicationType
Journal Article, Review