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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1979-7-25
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pubmed:abstractText |
Prolonged chair restraint and social isolation in the rhesus monkey led to a reduction in the urinary excretion of HVA (4-hydroxy-3-methoxyphenylacetic acid), DOPAC (3,4-dihydroxyphenylacetic acid), VMA methoxy-4-hydroxymandelic acid), and MHPG (3-methoxy-4-hydroxyphenylethylglycol) over a 3 week period. This adaptation to a chronically "stressful" situation corresponds to earlier studies on the rhesus monkey indicating a gradual reduction in the urinary excretion of norepinephrine and epinephrine after initiation of restraint. The following basic information on the urinary excretion of catecholamine metabolites was obtained: (1) the rate of excretion of the dopamine metabolites (HVA and DOPAC) is about four times higher than the rate of excretion of adrenergic metabolites (VMA and MHPG): (2) MHPG is the major adrenergic metabolite in the rhesus monkey; and (3) the excretion rates of the urinary metabolites varied considerably between animals.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0033-3174
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-45
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:108755-3,4-Dihydroxyphenylacetic Acid,
pubmed-meshheading:108755-Animals,
pubmed-meshheading:108755-Catecholamines,
pubmed-meshheading:108755-Haplorhini,
pubmed-meshheading:108755-Homovanillic Acid,
pubmed-meshheading:108755-Humans,
pubmed-meshheading:108755-Macaca,
pubmed-meshheading:108755-Macaca mulatta,
pubmed-meshheading:108755-Male,
pubmed-meshheading:108755-Methoxyhydroxyphenylglycol,
pubmed-meshheading:108755-Restraint, Physical,
pubmed-meshheading:108755-Social Isolation,
pubmed-meshheading:108755-Stress, Psychological,
pubmed-meshheading:108755-Time Factors,
pubmed-meshheading:108755-Vanilmandelic Acid
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pubmed:year |
1979
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pubmed:articleTitle |
Adrenergic and dopaminergic response to chronic chair restraint in the rhesus monkey.
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pubmed:publicationType |
Journal Article
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