Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-7-19
pubmed:abstractText
Nicotine at the dose level of 0.3 mg/100 g body weight was administered to normal cycling mice for 15 days through oral and intraperitoneal routes. At autopsy on 16th day significant reduction in the ovarian and uterine weight was observed. Histological observations showed decrease in the number and size of Graafian follicles, corpora lutea and increase in the atretic follicles in the ovary. The uterus showed absence of endometrial glands, decrease in the height of myometrium, endometrium and its epithelial cells. The total cholesterol content of the ovary and uterus is increased whereas the protein content is decreased. This antagonistic action of nicotine to gonadotrophins is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0019-5499
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
503-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Nicotine induced ovarian and uterine changes in albino mice.
pubmed:affiliation
Department of Zoology, Gulbarga University.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't