|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2000-9-13
|
|
pubmed:abstractText |
Gemcitabine (dFdC) is a new nucleoside antimetabolite of deoxycytidine that resembles cytarabine (Ara-C) in both its structure and metabolism. Little is known about dFdC efficacy in hematologic malignancies, either as a single drug or in combination with other drugs. In this study we have tried to determine whether the cytotoxic effect of Ara-C can be increased by using it in combined therapy with dFdC.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0390-6078
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
85
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
588-94
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10870114-Animals,
pubmed-meshheading:10870114-Antimetabolites, Antineoplastic,
pubmed-meshheading:10870114-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:10870114-Cell Culture Techniques,
pubmed-meshheading:10870114-Cytarabine,
pubmed-meshheading:10870114-Deoxycytidine,
pubmed-meshheading:10870114-Humans,
pubmed-meshheading:10870114-Leukemia, Experimental,
pubmed-meshheading:10870114-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:10870114-Male,
pubmed-meshheading:10870114-Mice,
pubmed-meshheading:10870114-Mice, Inbred Strains,
pubmed-meshheading:10870114-Stem Cells,
pubmed-meshheading:10870114-Tumor Cells, Cultured
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
The interaction of gemcitabine and cytarabine on murine leukemias L1210 or P388 and on human normal and leukemic cell growth in vitro.
|
|
pubmed:affiliation |
Department of Hematology, Medical University of Lodz, Poland.
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
