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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
25
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pubmed:dateCreated |
2000-7-19
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pubmed:abstractText |
We have recently demonstrated a lectin-like receptor for oxidized (ox)-LDL (LOX-1) in human coronary artery endothelial cells (HCAECs). This receptor is upregulated by ox-LDL. The present study examined the significance of LOX-1 in monocyte adhesion to HCAECs and endothelial injury in response to ox-LDL.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/L-Lactate Dehydrogenase,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/OLR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Oligonucleotides, Antisense,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Oxidized LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class E,
http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2889-95
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10869259-Cell Adhesion,
pubmed-meshheading:10869259-Cells, Cultured,
pubmed-meshheading:10869259-Chemokine CCL2,
pubmed-meshheading:10869259-Coronary Vessels,
pubmed-meshheading:10869259-Endothelium, Vascular,
pubmed-meshheading:10869259-Enzyme Activation,
pubmed-meshheading:10869259-Humans,
pubmed-meshheading:10869259-L-Lactate Dehydrogenase,
pubmed-meshheading:10869259-Lipoproteins, LDL,
pubmed-meshheading:10869259-Mitogen-Activated Protein Kinases,
pubmed-meshheading:10869259-Monocytes,
pubmed-meshheading:10869259-Oligonucleotides, Antisense,
pubmed-meshheading:10869259-Receptors, LDL,
pubmed-meshheading:10869259-Receptors, Oxidized LDL,
pubmed-meshheading:10869259-Scavenger Receptors, Class E,
pubmed-meshheading:10869259-Up-Regulation
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pubmed:year |
2000
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pubmed:articleTitle |
Antisense to LOX-1 inhibits oxidized LDL-mediated upregulation of monocyte chemoattractant protein-1 and monocyte adhesion to human coronary artery endothelial cells.
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pubmed:affiliation |
Departments of Medicine and Physiology, University of Florida and VA Medical Center, Gainesville, FL 32610, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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