Linked Life Data

1086902

Source:http://linkedlifedata.com/resource/pubmed/id/1086902

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-1-29
pubmed:abstractText
1. Electrical coupling between the cells of the crystalline lens of the frog eye was studied using two intralenticular micro-electrodes, one to pass current and one to record potential. In most experiments, both electrodes were placed just inside the posterior surface of the lens at a depth of approximately 200 mum from the surface. Step functions of current were applied and the time course of the resulting change in voltage was measured at many different electrode separations. 2. The voltage change has both a fast component, which occurs only locally in the region close to the current passing micro-electrode, and a slow component, which is spatially uniform, independent of distance from the current micro-electrode. 3. This behaviour is predicted by an electrical model of a single large spherical cell, and so that model can be used to analyse our data. 4. The resistivity of the lens 'interior' (both cytoplasm and coupling resistivity) is 625 omega cm; the resistance of the lens 'membrane' is 2751 omega cm2. 5. The data and analysis help to reconcile discrepancies between previous measurements of the electrical properties of the lens and show clearly that there is substantial electrical coupling from cell to cell. The method should allow investigation of the role of electrical coupling in cataract formation in the crystalline lens.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-1115005, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-1122997, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-13355944, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-13601016, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-4544153, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-4547546, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-4583658, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-4593247, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-4692234, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-5229810, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-5358236, http://linkedlifedata.com/resource/pubmed/commentcorrection/1086902-5424376
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:volume
262
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
285-300
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Current-voltage relationships in the crystalline lens.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.