|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2000-7-13
|
|
pubmed:abstractText |
Cytomegalovirus (CMV) is a ubiquitous herpesvirus that infects 50-90% of individuals in different populations. After primary infection, the virus persists latently in myeloid cells under the control of specific T-cells. Reactivation of CMV infection may cause lethal organ dysfunction and is frequently seen in immunosuppressed individuals. CD8+ cytotoxic T-cells (CTL) have a primary role in suppressing CMV reactivation, and the dominating CTL response is directed against pp65.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0041-1337
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
69
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2243-50
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10868621-Adult,
pubmed-meshheading:10868621-Biological Markers,
pubmed-meshheading:10868621-Blood Cells,
pubmed-meshheading:10868621-CD8-Positive T-Lymphocytes,
pubmed-meshheading:10868621-Cell Line,
pubmed-meshheading:10868621-Female,
pubmed-meshheading:10868621-HLA-A2 Antigen,
pubmed-meshheading:10868621-Humans,
pubmed-meshheading:10868621-Kidney Transplantation,
pubmed-meshheading:10868621-Major Histocompatibility Complex,
pubmed-meshheading:10868621-Phosphoproteins,
pubmed-meshheading:10868621-Reference Values,
pubmed-meshheading:10868621-Staining and Labeling,
pubmed-meshheading:10868621-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:10868621-Viral Matrix Proteins
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Characterization of CMVpp65-specific CD8+ T lymphocytes using MHC tetramers in kidney transplant patients and healthy participants.
|
|
pubmed:affiliation |
Division of Clinical Immunology & Transfusion Medicine, University Hospital, Uppsala, Sweden.
|
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|
