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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2000-9-12
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pubmed:abstractText |
The staphylococcal protein A (SPA) column used to treat refractory autoimmune and alloimmune thrombocytopenia and rheumatoid arthritis patients is primed with heparin to prevent possible fibrin clot formation when the patient's plasma is passed through the column. A BMT patient with refractory alloimmune thrombocytopenia had prolonged activated partial thromboplastin times (aPTTs) at the end of SPA column treatments. This observation led to in vivo and in vitro analysis of the kinetics of heparin elution from the SPA column.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0041-1132
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
697-701
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10864991-Anticoagulants,
pubmed-meshheading:10864991-Antigen-Antibody Complex,
pubmed-meshheading:10864991-Arthritis, Rheumatoid,
pubmed-meshheading:10864991-Autoimmune Diseases,
pubmed-meshheading:10864991-Chromatography, Affinity,
pubmed-meshheading:10864991-Hemorrhagic Disorders,
pubmed-meshheading:10864991-Heparin,
pubmed-meshheading:10864991-Humans,
pubmed-meshheading:10864991-Immunoglobulin G,
pubmed-meshheading:10864991-Immunosorbent Techniques,
pubmed-meshheading:10864991-Isoantibodies,
pubmed-meshheading:10864991-Partial Thromboplastin Time,
pubmed-meshheading:10864991-Staphylococcal Protein A,
pubmed-meshheading:10864991-Thrombocytopenia
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pubmed:year |
2000
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pubmed:articleTitle |
Heparin-induced coagulopathy associated with staphylococcal protein A immunoadsorption treatment columns: an in vitro and in vivo analysis.
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pubmed:affiliation |
Blood Bank-Transfusion Medicine Service, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA.
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pubmed:publicationType |
Journal Article
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