| pubmed-article:10864103 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10864103 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:10864103 | lifeskim:mentions | umls-concept:C0015859 | lld:lifeskim |
| pubmed-article:10864103 | lifeskim:mentions | umls-concept:C0699819 | lld:lifeskim |
| pubmed-article:10864103 | lifeskim:mentions | umls-concept:C0597357 | lld:lifeskim |
| pubmed-article:10864103 | lifeskim:mentions | umls-concept:C1510470 | lld:lifeskim |
| pubmed-article:10864103 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:10864103 | pubmed:issue | 24 | lld:pubmed |
| pubmed-article:10864103 | pubmed:dateCreated | 2000-7-13 | lld:pubmed |
| pubmed-article:10864103 | pubmed:abstractText | The role of 5-hydroxytryptamine (5-HT)3 and 5-HT4 receptors in the regulation of gut motility in the ferret was investigated. The selective 5-HT3 receptor antagonist ramosetron (1 - 10 microg/kg s.c.) prolonged the interval of gastric antral migrating motor complex, but had only slight effect on small intestinal and colonic motility in unfed animals. The selective 5-HT4 receptor antagonist SB 204070 did not affect motility throughout gut in unfed animals. Neither ramosetron nor SB 204070 affected the motility throughout gut in fed animals. In conclusion, neither 5-HT3 nor 5-HT4 receptors tonically regulate ferret gut motility except that 5-HT3 receptors have a key role in the occurrence of migrating motor complex specifically in the stomach. The role of 5-HT3 and 5-HT4 receptor system in the regulation of gut motility in ferrets is similar to that in other mammalian species studied, including humans. This similarity suggests that the ferret is a suitable model animal to study gut motor functions in humans. | lld:pubmed |
| pubmed-article:10864103 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10864103 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10864103 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10864103 | pubmed:month | May | lld:pubmed |
| pubmed-article:10864103 | pubmed:issn | 0024-3205 | lld:pubmed |
| pubmed-article:10864103 | pubmed:author | pubmed-author:YamaguchiTT | lld:pubmed |
| pubmed-article:10864103 | pubmed:author | pubmed-author:ItoHH | lld:pubmed |
| pubmed-article:10864103 | pubmed:author | pubmed-author:MiyataKK | lld:pubmed |
| pubmed-article:10864103 | pubmed:author | pubmed-author:KissPP | lld:pubmed |
| pubmed-article:10864103 | pubmed:author | pubmed-author:NagakuraYY | lld:pubmed |
| pubmed-article:10864103 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10864103 | pubmed:day | 5 | lld:pubmed |
| pubmed-article:10864103 | pubmed:volume | 66 | lld:pubmed |
| pubmed-article:10864103 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10864103 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10864103 | pubmed:pagination | PL331-8 | lld:pubmed |
| pubmed-article:10864103 | pubmed:dateRevised | 2003-11-14 | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:meshHeading | pubmed-meshheading:10864103... | lld:pubmed |
| pubmed-article:10864103 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10864103 | pubmed:articleTitle | The role of 5-hydroxytryptamine3 and 5-hydroxytryptamine4 receptors in the regulation of gut motility in the ferret. | lld:pubmed |
| pubmed-article:10864103 | pubmed:affiliation | Neuroscience Research, Pharmacology Laboratories, Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan. | lld:pubmed |
| pubmed-article:10864103 | pubmed:publicationType | Journal Article | lld:pubmed |
