10857794

Source:http://linkedlifedata.com/resource/pubmed/id/10857794

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C1862852
pubmed:issue	6
pubmed:dateCreated	2000-6-30
pubmed:abstractText	Ankylosing spondylitis (AS) affects 0.25-1.0% of the population, and its etiology is incompletely understood. Susceptibility to this highly familial disease (lambda(s) = 58) is primarily genetically determined. There is a significant sex bias in AS, and there are differences in recurrence risk to the offspring of affected mothers and fathers, suggesting that there may be an X-linked recessive effect. We undertook an X-chromosome linkage study to determine any contribution of the X-chromosome to AS susceptibility.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370605
pubmed:citationSubset	AIM
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	0004-3591
pubmed:author	pubmed-author:BrownM AMA, pubmed-author:CalinAA, pubmed-author:HoyleEE, pubmed-author:LavalS HSH, pubmed-author:WordsworthB PBP
pubmed:issnType	Print
pubmed:volume	43
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1353-5
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:10857794-Genetic Linkage, pubmed-meshheading:10857794-Genetic Predisposition to Disease, pubmed-meshheading:10857794-Humans, pubmed-meshheading:10857794-Lod Score, pubmed-meshheading:10857794-Spondylitis, Ankylosing, pubmed-meshheading:10857794-X Chromosome
pubmed:year	2000
pubmed:articleTitle	The X-chromosome and susceptibility to ankylosing spondylitis.
pubmed:affiliation	Wellcome Trust Centre for Human Genetics, Headington, UK.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't