Source:http://linkedlifedata.com/resource/pubmed/id/10857011
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
2000-7-7
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| pubmed:abstractText |
Spontaneous viral encephalitis is rare in the baboon; yet, during a 13-month period (1993-1994), eight juvenile baboons (Papio cynocephalus spp.) developed acute, progressive nonsuppurative meningoencephalomyelitis caused by an unknown agent. Clinical signs of disease included disorientation and truncal ataxia that rapidly progressed to hemiparesis or paraparesis. Clinicopathologic findings were not remarkable and appreciable gross lesions were not seen at necropsy. Microscopic examination revealed CNS lesions that were characterized by lymphoplasmacytic perivascular cuffing, microglial nodules, demyelination, axonal degeneration, vacuolization, and hemorrhage. Subsequently, a novel syncytium-inducing mammalian orthoreovirus was isolated from the brain tissue of five baboons with clinical signs of infection.
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| pubmed:grant | |
| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
1532-0820
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
50
|
| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
199-205
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| pubmed:dateRevised |
2011-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10857011-Animals,
pubmed-meshheading:10857011-Animals, Laboratory,
pubmed-meshheading:10857011-Biological Assay,
pubmed-meshheading:10857011-Brain,
pubmed-meshheading:10857011-Cercopithecus aethiops,
pubmed-meshheading:10857011-Disease Outbreaks,
pubmed-meshheading:10857011-Female,
pubmed-meshheading:10857011-Housing, Animal,
pubmed-meshheading:10857011-Male,
pubmed-meshheading:10857011-Meninges,
pubmed-meshheading:10857011-Meningitis, Viral,
pubmed-meshheading:10857011-Meningoencephalitis,
pubmed-meshheading:10857011-Mice,
pubmed-meshheading:10857011-Monkey Diseases,
pubmed-meshheading:10857011-Orthoreovirus,
pubmed-meshheading:10857011-Papio,
pubmed-meshheading:10857011-Rats,
pubmed-meshheading:10857011-Serologic Tests,
pubmed-meshheading:10857011-Spinal Cord,
pubmed-meshheading:10857011-Texas,
pubmed-meshheading:10857011-Vero Cells,
pubmed-meshheading:10857011-Viral Plaque Assay
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| pubmed:year |
2000
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| pubmed:articleTitle |
Outbreak of Orthoreovirus-induced meningoencephalomyelitis in baboons.
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| pubmed:affiliation |
Department of Physiology and Medicine, Southwest Foundation for Biomedical Research, San Antonio, TX, USA.
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| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|