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rdf:type |
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lifeskim:mentions |
umls-concept:C0004037,
umls-concept:C0006279,
umls-concept:C0014597,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0038027,
umls-concept:C0079323,
umls-concept:C0205148,
umls-concept:C0443307,
umls-concept:C0449432,
umls-concept:C1167622,
umls-concept:C1179435,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1705248,
umls-concept:C1882727,
umls-concept:C2349975
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pubmed:issue |
7
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pubmed:dateCreated |
2000-7-21
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pubmed:abstractText |
Aspergillus fumigatus is a pathogenic fungus which causes a range of diseases, particularly in the human lung. The pathological mechanism is unknown but may involve a complex mixture of biomolecules which can diffuse from the spore surface. This material is known as A fumigatus diffusate (AfD) and has previously been shown to have a range of immunosuppressive functions. It is hypothesised that AfD may influence the binding of spores to extracellular matrix (ECM) proteins and lung epithelial cells, thereby affecting the ability of the fungus to cause infection.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-10047533,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-10456901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-2229838,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-2258912,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-2564961,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-3310309,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-3325630,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-5432063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-6387001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-7510665,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-7642568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-780000,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-8036299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-8188338,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-8520747,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-8679226,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-8733491,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-8945572,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-8994516,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-9119494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-9163329,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-9813381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10856318-9813383
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0040-6376
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-84
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:10856318-Animals,
pubmed-meshheading:10856318-Aspergillosis,
pubmed-meshheading:10856318-Aspergillus fumigatus,
pubmed-meshheading:10856318-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:10856318-Collagen,
pubmed-meshheading:10856318-Epithelial Cells,
pubmed-meshheading:10856318-Extracellular Matrix Proteins,
pubmed-meshheading:10856318-Fibronectins,
pubmed-meshheading:10856318-Laminin,
pubmed-meshheading:10856318-Rats,
pubmed-meshheading:10856318-Rats, Wistar,
pubmed-meshheading:10856318-Spores
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pubmed:year |
2000
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pubmed:articleTitle |
Enhanced binding of Aspergillus fumigatus spores to A549 epithelial cells and extracellular matrix proteins by a component from the spore surface and inhibition by rat lung lavage fluid.
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pubmed:affiliation |
Biomedicine Research Group, School of Life Sciences, Napier University, Edinburgh EH10 5DT, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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