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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2000-11-15
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pubmed:abstractText |
A series of 5-(2- or 3-thienyl)tryptamine derivatives (9) has been synthesized and shown to be potent and selective 5-HT1D versus 5-HT1B receptor agonists and, therefore, potential treatments for migraine.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/HTR1B protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Indicators and Reagents,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Serotonin, 5-HT1B,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Serotonin, 5-HT1D,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Serotonin,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Tryptamines
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
903-5
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:10853656-Cloning, Molecular,
pubmed-meshheading:10853656-Humans,
pubmed-meshheading:10853656-Indicators and Reagents,
pubmed-meshheading:10853656-Migraine Disorders,
pubmed-meshheading:10853656-Receptor, Serotonin, 5-HT1B,
pubmed-meshheading:10853656-Receptor, Serotonin, 5-HT1D,
pubmed-meshheading:10853656-Receptors, Serotonin,
pubmed-meshheading:10853656-Serotonin Antagonists,
pubmed-meshheading:10853656-Structure-Activity Relationship,
pubmed-meshheading:10853656-Tryptamines
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pubmed:year |
2000
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pubmed:articleTitle |
5-Thienyltryptamine derivatives as serotonin 5-HT1B/1D receptor agonists: potential treatments for migraine.
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pubmed:affiliation |
NPS Allelix Corp., Mississauga, Ontario, Canada. cmeng@atherogenics.com
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pubmed:publicationType |
Journal Article
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