|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2000-11-15
|
|
pubmed:abstractText |
A direct synthesis of analogues 6 and 7 is described. The key transformations are the addition of dibromomethyl lithium to a ketone and the subsequent mild hydrolysis to a hemiacetal.
|
|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0960-894X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
10
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
895-7
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10853654-Acetonitriles,
pubmed-meshheading:10853654-Acylation,
pubmed-meshheading:10853654-Animals,
pubmed-meshheading:10853654-Humans,
pubmed-meshheading:10853654-Rabbits,
pubmed-meshheading:10853654-Receptor, Endothelin A,
pubmed-meshheading:10853654-Receptor, Endothelin B,
pubmed-meshheading:10853654-Receptors, Endothelin,
pubmed-meshheading:10853654-Tetrahydronaphthalenes
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Synthesis and endothelin receptor binding activity of synthetic analogues of RES-1149-2.
|
|
pubmed:affiliation |
Department of Chemistry, Iowa State University, Ames 50011, USA. gakraus@iastate.edu
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
|
