| pubmed-article:10853653 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10853653 | lifeskim:mentions | umls-concept:C0023779 | lld:lifeskim |
| pubmed-article:10853653 | lifeskim:mentions | umls-concept:C0042890 | lld:lifeskim |
| pubmed-article:10853653 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:10853653 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
| pubmed-article:10853653 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:10853653 | lifeskim:mentions | umls-concept:C1524066 | lld:lifeskim |
| pubmed-article:10853653 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:10853653 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:10853653 | pubmed:dateCreated | 2000-11-15 | lld:pubmed |
| pubmed-article:10853653 | pubmed:abstractText | A new panel of steroidal cationic lipids has been synthesized for gene delivery. Using commercially available vitamin D2 (calciferol) or vitamin D3 (cholecalciferol) as hydrophobic motifs and a variety of cationic head groups as binding sites for negatively charged phosphate groups in DNA, we demonstrated that the transfection activity of the synthetic vitamin D-based cationic lipids 1d, 2d formulated with dioleoylphosphatidylethanolamine (DOPE) as a co-lipid is comparable to that of 3-(-[N-N',N'-dimethylaminoethane)carbamoyl]cholesterol (DC-Chol). These synthetic lipids are effective in transfecting a variety of cell lines. These results suggest that vitamin D-based cationic lipids are useful transfection reagents for in vitro gene transfer studies. | lld:pubmed |
| pubmed-article:10853653 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853653 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10853653 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853653 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10853653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853653 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10853653 | pubmed:month | May | lld:pubmed |
| pubmed-article:10853653 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:10853653 | pubmed:author | pubmed-author:ReaAA | lld:pubmed |
| pubmed-article:10853653 | pubmed:author | pubmed-author:LisHH | lld:pubmed |
| pubmed-article:10853653 | pubmed:author | pubmed-author:LieTT | lld:pubmed |
| pubmed-article:10853653 | pubmed:author | pubmed-author:ZhangGG | lld:pubmed |
| pubmed-article:10853653 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10853653 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:10853653 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:10853653 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10853653 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10853653 | pubmed:pagination | 891-4 | lld:pubmed |
| pubmed-article:10853653 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:10853653 | pubmed:meshHeading | pubmed-meshheading:10853653... | lld:pubmed |
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| pubmed-article:10853653 | pubmed:meshHeading | pubmed-meshheading:10853653... | lld:pubmed |
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| pubmed-article:10853653 | pubmed:meshHeading | pubmed-meshheading:10853653... | lld:pubmed |
| pubmed-article:10853653 | pubmed:meshHeading | pubmed-meshheading:10853653... | lld:pubmed |
| pubmed-article:10853653 | pubmed:meshHeading | pubmed-meshheading:10853653... | lld:pubmed |
| pubmed-article:10853653 | pubmed:meshHeading | pubmed-meshheading:10853653... | lld:pubmed |
| pubmed-article:10853653 | pubmed:meshHeading | pubmed-meshheading:10853653... | lld:pubmed |
| pubmed-article:10853653 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10853653 | pubmed:articleTitle | Synthesis and evaluation of vitamin D-based cationic lipids for gene delivery in vitro. | lld:pubmed |
| pubmed-article:10853653 | pubmed:affiliation | Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA. | lld:pubmed |
| pubmed-article:10853653 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10853653 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10853653 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:10853653 | lld:chembl |
