Source:http://linkedlifedata.com/resource/pubmed/id/10853649
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
2000-11-15
|
| pubmed:abstractText |
2-methylfuro[2,3-g]isoquinoline-4,7,9-trione (4) and 2-methylfuro[3,2-g]isoquinoline-4,6,9-trione (5) were prepared regiospecifically from 2-azadiene 9 and bromobenzofuran-4,7-diones 1 or 11. The activity of these two compounds and some other quinonic derivatives was evaluated in vitro against a virulent strain of Toxoplasma gondii. Compounds 4 and 7 were found to be as active as pyrimethamine.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
10
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
871-3
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:10853649-Animals,
pubmed-meshheading:10853649-Antiprotozoal Agents,
pubmed-meshheading:10853649-Cell Line,
pubmed-meshheading:10853649-Furans,
pubmed-meshheading:10853649-Humans,
pubmed-meshheading:10853649-Monocytes,
pubmed-meshheading:10853649-Quinolines,
pubmed-meshheading:10853649-Toxoplasma
|
| pubmed:year |
2000
|
| pubmed:articleTitle |
Quinonic derivatives active against a virulent strain of Toxoplasma gondii. Synthesis of 2-methylfuro[2,3-g]- and [3,2-g]isoquinolinetriones.
|
| pubmed:affiliation |
Laboratoire de Chimie Organique EA 635, Université Claude Bernard, Faculté de Pharmacie, Lyon, France.
|
| pubmed:publicationType |
Journal Article
|