| pubmed-article:10853270 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C0038975 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C2350483 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C0008169 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C0450240 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C1706210 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C2347567 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C1523987 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C1519595 | lld:lifeskim |
| pubmed-article:10853270 | lifeskim:mentions | umls-concept:C0887917 | lld:lifeskim |
| pubmed-article:10853270 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10853270 | pubmed:dateCreated | 2000-10-16 | lld:pubmed |
| pubmed-article:10853270 | pubmed:abstractText | The bacterial gene chloramphenicol acetyltransferase (CAT) is a widely used reporter in both in-vitro and in-vivo studies of genetic regulation. We have recently generated novel rat transgenic lines carrying an arylalkylamine N-acetyltransferase (AA-NAT) promoter-reporter construct in which CAT (with associated SV40 small-t antigen sequence) is the reporter. In addition to the predicted transgene transcript (1.9 kb), we identified an abundant 1.5 kb transcript which derives from an alternative splicing event that utilises a cryptic splice donor site located within the CAT gene. The native CAT open reading frame (ORF) is lost in the 1.5 kb transcript, and a western analysis has shown that protein deriving from an aberrant open reading frame is not expressed at detectable levels. | lld:pubmed |
| pubmed-article:10853270 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10853270 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853270 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10853270 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853270 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853270 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10853270 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10853270 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:10853270 | pubmed:issn | 0962-8819 | lld:pubmed |
| pubmed-article:10853270 | pubmed:author | pubmed-author:CarterD ADA | lld:pubmed |
| pubmed-article:10853270 | pubmed:author | pubmed-author:WellsTT | lld:pubmed |
| pubmed-article:10853270 | pubmed:author | pubmed-author:BalerRR | lld:pubmed |
| pubmed-article:10853270 | pubmed:author | pubmed-author:BurkeZ DZD | lld:pubmed |
| pubmed-article:10853270 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10853270 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:10853270 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10853270 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10853270 | pubmed:pagination | 67-70 | lld:pubmed |
| pubmed-article:10853270 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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| pubmed-article:10853270 | pubmed:meshHeading | pubmed-meshheading:10853270... | lld:pubmed |
| pubmed-article:10853270 | pubmed:year | 2000 | lld:pubmed |
| pubmed-article:10853270 | pubmed:articleTitle | Use of a cryptic splice donor site in the chloramphenicol acetyltransferase (CAT)-SV40 small-t antigen cassette generates alternative transcripts in transgenic rats. | lld:pubmed |
| pubmed-article:10853270 | pubmed:affiliation | School of Biosciences, Cardiff University, UK. smbdac@cardiff.ac.uk | lld:pubmed |
| pubmed-article:10853270 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10853270 | lld:pubmed |
