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rdf:type |
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lifeskim:mentions |
umls-concept:C0005516,
umls-concept:C0017262,
umls-concept:C0018787,
umls-concept:C0024264,
umls-concept:C0035015,
umls-concept:C0185117,
umls-concept:C0205217,
umls-concept:C0205462,
umls-concept:C0229664,
umls-concept:C0332120,
umls-concept:C0450127,
umls-concept:C1413235,
umls-concept:C1548437,
umls-concept:C1879547,
umls-concept:C1882923,
umls-concept:C2911684
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pubmed:issue |
10
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pubmed:dateCreated |
2000-6-23
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pubmed:abstractText |
The human leukocyte membrane protein CD69 is an early activation marker induced in T lymphocytes, B cells, and natural killer cells in response to inflammatory stimuli. Cardiac catheterization and endomyocardial biopsy remain the "gold standard" for diagnosis of rejection after transplantation, and noninvasive methods of rejection surveillance have long been sought. We studied CD69 membrane protein expression in peripheral blood T lymphocytes obtained from pediatric cardiac transplant recipients at the time of biopsy and correlated the results with histologic rejection scores.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2102-7
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10852605-Adolescent,
pubmed-meshheading:10852605-Adult,
pubmed-meshheading:10852605-Antigens, CD,
pubmed-meshheading:10852605-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:10852605-B-Lymphocytes,
pubmed-meshheading:10852605-Biological Markers,
pubmed-meshheading:10852605-Biopsy,
pubmed-meshheading:10852605-CD4-Positive T-Lymphocytes,
pubmed-meshheading:10852605-CD8-Positive T-Lymphocytes,
pubmed-meshheading:10852605-Child,
pubmed-meshheading:10852605-Flow Cytometry,
pubmed-meshheading:10852605-Graft Rejection,
pubmed-meshheading:10852605-Heart Transplantation,
pubmed-meshheading:10852605-Humans,
pubmed-meshheading:10852605-Lectins, C-Type,
pubmed-meshheading:10852605-Lymphocyte Activation,
pubmed-meshheading:10852605-T-Lymphocytes,
pubmed-meshheading:10852605-Transplantation, Homologous
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pubmed:year |
2000
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pubmed:articleTitle |
Increased expression of the lymphocyte early activation marker CD69 in peripheral blood correlates with histologic evidence of cardiac allograft rejection.
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pubmed:affiliation |
Department of Pediatrics (Cardiology), University of Florida College of Medicine, Gainesville 32610, USA. schowko@peds.ufl.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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