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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2000-7-13
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pubmed:abstractText |
Four of 10 patients who were enrolled on protocols of high-dose immunosuppression with peripheral blood stem cell rescue for MS experienced neurologic worsening while receiving recombinant human granulocyte colony-stimulating factor. There was improvement when methylprednisolone was given to three of the patients, but one patient died of respiratory failure. The mechanism of the neurologic worsening is uncertain.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0028-3878
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2147-50
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:10851379-Adult,
pubmed-meshheading:10851379-Anti-Inflammatory Agents,
pubmed-meshheading:10851379-Female,
pubmed-meshheading:10851379-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:10851379-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:10851379-Humans,
pubmed-meshheading:10851379-Male,
pubmed-meshheading:10851379-Methylprednisolone,
pubmed-meshheading:10851379-Middle Aged,
pubmed-meshheading:10851379-Multiple Sclerosis,
pubmed-meshheading:10851379-Paralysis,
pubmed-meshheading:10851379-Recombinant Proteins
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pubmed:year |
2000
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pubmed:articleTitle |
Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor.
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pubmed:affiliation |
Department of Neurology, City of Hope National Medical Center, Duarte, CA 91010, USA. hopenshaw@coh.org
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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